That sounds heartbreaking. I might be on my way to a similar decision. What strikes me is the loneliness of living with someone and feeling like their presence is increasingly empty/estranged – like they’re in a bubble and I can’t get in (well, I could join in but I don’t want to) and they can’t get out. Your feeling of guilt is understandable, but you shouldn’t feel guilty – there comes a point when you need to look after yourself. Your emotional/mental well-being, your life, is just as important as theirs. You have done your best to help this person, but only they can make the changes/choices to seek support for their addiction and/or to give up the substance use. I wonder if, in some cases, leaving someone might actually be the push/wake-up call a person might need in order for them to initiate change.